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FlowJo software is used for the analysis of flow cytometry data. This tutorial will introduce you to FlowJo using a simple experiment as an example. A FITC anti-CD8 reagent is titrated to determine the most economical concentration for staining in future experiments. Table of Contents Introduction Step 1: Load samples into the workspace Step 2: Analyze the control sample in detail Step 3: Copy gates and statistics to all samples Step 4: Verify gates on all samples Continue to download »

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The genetic factors underlying common disease are largely unknown. Discovery of disease causing genes will transform our knowledge of the genetic contribution to human disease, lead to new genetic screens, and underpin research into new cures and improved lifestyles. The sequencing of the human genome has catalyzed efforts to search for disease genes by the strategy of associating sequence variants with measurable phenotypes. In particular, the Human Genome Project and follow-on efforts to Continue to download »

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Charles I. Jones John C. Williams Abstract Is there too much or too little private research and development (R&D)? A large empirical literature reports estimates of the rate of return to R&D ranging from 30% to over 100%, supporting the notion that there is too little private investment in research. However, this conclusion is challenged by the new growth theory, which emphasizes a richer description of the connection between R&D and Continue to download »

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Despite previous efforts in auditing software manually and automatically, buffer overruns are still being discovered in programs in use. A dynamic bounds checker detects buffer overruns in erroneous software before it occurs and thereby prevents attacks from corrupting the integrity of the system. Dynamic buffer overrun detectors have not been adopted widely because they either  (1) cannot guard against all buffer overrun attacks (2) Continue to download »

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The goal of our research is to provide programming language support for exploiting coarse-grain concurrency, or concurrency in which each unit of serial computation executes at least several thousand instructions. There are two major reasons why automatic techniques that extract static parallelism from sequential programs cannot fully exploit available Continue to download »