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Hearing loss is relatively common in the human population. Profound congenital hearing loss is estimated to occur in about 1 in 1000 births; approximately 50% of cases are thought to be due to environmental factors and the remainder to genetic causes1,2 (Fig. 1). Examples of the former include acoustic trauma, ototoxic drug exposure (i.e., aminoglycosides), and bacterial or viral infec- tions such as rubella or cytomegalovirus Continue to download »

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More About Molecular Genetics In 1992 the American Association for the Advancement of Science conducted an opinion poll of members, asking what scientific specialty holds the greatest promise over the next decade. “Genetics” or “molecular and cell biology,” or both, were listed most often by biologists, medical scientists, social/ behavioral scientists, chemists, and physicists/astronomers— even more often than their own specialties. Continue to download »

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Some theories of intelligence extend this de?nition by suggesting that there is a general factor of intelligence, often labeled g, that underlies all adaptive behavior (Brand, 1996; Jensen, 1998; see essays in Sternberg & Grigorenko, 2002b). In many theories, including the theories most widely accepted today (e.g., Carroll, 1993; Gustafsson, 1994; Horn, 1994), other Continue to download »

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BEST: A Novel Computational Approach for Comparing Gene Expression Patterns From Early Stages of Drosophila melanogaster Development Embryonic gene expression patterns are an indispensable part of modern developmental biology. Currently, investigators must visually inspect numerous images containing embryonic expression patterns to identify Continue to download »

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The majority of genetics and health insurance laws—with the exception of laws that address coverage of newborn screening and rare childhood genetic diseases—focus on public perceptions that health insurers will use genetic information to deny coverage or charge higher rates based on genetic information or genetic test results. Some observers argue that Continue to download »